Cyclic GMP-AMP (cGAMP) synthase (cGAS), a sensor of cytosolic DNA, recognizes cytoplasmic nucleic acids to activate the innate immune responses via generation of the second messenger cGAMP and subsequent activation of the stimulator Dishwasher Cup Rack of interferon genes (STINGs).The cGAS-STING signaling has multiple immunologic and physiological
From STEM-EDXS data to phase separation and quantification using physics-guided NMF
We present the development of a new algorithm which combines state-of-the-art energy-dispersive x-ray (EDX) spectroscopy theory and a suitable machine learning formulation for the hyperspectral unmixing of scanning transmission electron microscope EDX spectrum images.The algorithm is based on non-negative matrix factorization (NMF) incorporating a
Spatial Analysis of Agricultural Landscape and Hymenoptera Biodiversity at Cianjur Watershed
Hymenoptera is one of the four largest insect order (the other three are Coleoptera, Banjo Strings Diptera, and Lepidoptera).There are curerently over 115 000 described Hymenoptera species.It is clear that Hymenoptera is one of the major components of insect biodiversity.However, Hymenoptera biodiversity is affected by ecology, environment, and eco
The Impact of Consumer Ethnocentrism on Purchase Intentions: Local Versus Foreign Brands
This study evaluates the impact of consumer constructs, including ethnocentrism, attitudes toward brands, and celebrity endorsement, on purchase intentions cardigans for beverages in Pakistan.A quantitative survey was administered to collect the data and a path analysis conducted to test the model.Based on a sample of 150 respondents, our results i
Anger can make fake news viral online
Fake news that manipulates political elections, strikes financial systems, and even incites riots is more viral than real news online, resulting in unstable societies and buffeted democracy.While factor that drives the viral spread of fake news is rarely explored.In this study, it is unexpectedly found that the easier contagion of fake news online